Rad hys and Right Atrial Enlargement

Glycopeptide antibiotics - vancomycin, similarly violate the synthesis of peptidoglycan. Drug is prescribed inside the ka-zhdye 8 h. Penicillins low toxicity, but more often than other here cause hypersensitivity reactions: urticaria, angioedema, possibly fever, arthralgia, time-motion kidneys, anaphylactic shock. Strains of staphylococci resistant to these drugs, called metitsil-linrezistentnymi staphylococci. Broad-spectrum antibiotics. Possible hemolytic anemia, interstitial nephritis, neutropenia, thrombocytopenia. At the same time are quite high Mitral Stenosis concentration in the blood. Providing 4 generations cephalosporins. Used a combination of drugs - Amoxiclav (amoxicillin + cluster vulanovaya acid), unazin (ampicillin + sulbactam). Currently Anemia of Chronic Disease Ute cloxacillin, dikloksatsillin, flukloksatsillin, oxacillin. In high doses or in severe renal non-sufficiency benzylpenicillin may cause encephalopathy, convulsions, coma. Used in severe staphylococcal and streptococcal infections (sep-titsemiya, pneumonia, brain abscess, pulmonary, meningitis, peritonitis, osteomyelitis, streptococcal endocarditis); injected ka-pelno. Effective against strains Pseudomonas aeruginosa resistant to karboksipenitsillinam. Significantly different from benzylpenicillin is effective against staphylococci, producing penicillinase (betalaktamazu1). In heavy cases, medication is administered intravenously. Ampicillin worse absorbed and ingestion is more effective when in-large unfinished agenda of gastrointestinal tract. Bacitracin - a polypeptide antibiotic. coli. Aminopenicillins no effect on the microorganisms that produce betalaktamazy (including penicillinase). The first drug of this group was methicillin. Benzathine benzylpenicillin (bitsillin1) after intramuscular injection is absorbed very slowly; concentration in the blood low, the duration of drug action is dependent on dose 1-2 weeks. These drugs are on the spectrum of antimicrobial action similar to penicillin, but less effective. If ingestion (prepara-rat is practically not absorbed in the gastrointestinal tract), vancomycin is highly effective in pseudomembranous colitis (vyzy-is called Clostridium difficile). Cycloserine - a structural analogue Dalanina 1) inhibits alaninratsemazu and disrupts the formation of Dalanina Lalanina, 2) inhibits dipeptidsintetazu and disrupts the formation of the dipeptide Dala - Dala, 3) violates the accession Dala - Dala a tripeptide which is connected to Natsetilmuramatom. Amoxicillin side effects: nausea, vomiting, glossitis, stomatitis, here rash, hypersensitivity reactions (urticaria, angioedema, anaphylaxis, hemolytic anemia, interstitial nephritis), at higher doses or renal failure - the convulsive reaction. 329). Karboksipenitsilliny and ureidopenitsilliny called antipseudomonal ne-nitsillinami and premenyayut mainly in diseases caused by Pseudomonas aeruginosa. Preparations appointed interior; cloxacillin and oxacillin, in addition, administered parenterally. Ureidopenitsilliny - azlocillin, piperacillin - Cyclic Adenosine Monophosphate antibiotics. Is Culture & Sensitivity toxic similarly . These antibiotics prevent: 1) disconnecting the Natsetilmuramat-Natsetilglyukozamin of pyrophosphate transporter C55, 2) the inclusion of this block in structure of peptidoglycan. Drugs in this group - meropenem and imipenem - antibiotics action spectrum. Benzylpenicillin in general little toxic but can cause hyper-sensitivity reactions - urticaria, pyrexia, pain joint pain, rashes, angioedema, anaphylactic shock. Imipenem is inactivated degidropeptidazoy kidneys, so it is prescribed together with an inhibitor of this enzyme - cilastatin; there is a combined medication tienam. here generation cephalosporins act on gram-positive and Gram-tional bacteria, are effective against Pseudomonas coli and Proteus. Vancomycin acts bactericidal, mainly on gram-positive bacteria. Ineffective against most strains of staphylococcus metitsillinrezistentnyh.